In heart failure, self-care behavior is an independent determinant of health-related quality of life, regardless of the severity of this patients

Abstract Background Poor self-care behaviour is associated with a higher risk of readmission and mortality in patients heart failure (HF). The interplay between patient-reported outcomes such as health-related quality life (QoL) has not been fully established. Purpose To describe the association QoL real-world cohort HF patients. Methods We conducted an observational, prospective, study 1120 consecutive chronic HF. used modified European Heart Failure Self-care Behaviour Scale 9-item version (EHFSCBS-9) to measure self-care. Scores were inverted standardized (higher scores indicate better selfcare). assess QoL, we Minnesota Living Questionnaire (MLHFQ) worse QoL). Written informed consent, complete clinical psychosocial information obtained at baseline. determine impact global its dimensions (autonomy-based adherence, consulting provider-based adherence), multivariate linear regressions models (backwards stepwise methods) predict constructed. parametric non-parametric associations EHFSCBS-9 scoresand β estimated impairment (defined MLHFQ ≥ median values) explored using General Additive Models (GAM). All adjusted by age, sex prognostic factors LVEF, NYHA, NT-proBNP levels recent hospitalization among other well-known determinants severity. Results A total 484 (43%) women, mean age was 72±11 years, LVEF 45±17%. Mean 45±24. 69±28. There significant inverse correlation EHFScBS-9 (r=−0.158; p-value<0.0001). As shown Table 1, 3 domains independent predictors 7 out 16 explored. These confirmed weak relationship particularly selfcare dimension global, emotional social QoL. Interestingly, when dichotomized impaired/preserved GAM showed “U-shape” (p-value<0.05) (Figure 1). Conclusions have that predictor health related regardless level disease Global significantly Interestingly impaired non-linear showing pointing extreme more likely experience impairments Funding Acknowledgement Type funding sources: None.